LifeSciences ScienceLife

LifeSciences ScienceLife

By the Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences (PhaNuSpo), University of ViennaScienceEducationSelf-Improvement
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LifeSciences ScienceLife episodes

  • E19: The importance of pharmacology education in the age of misinformation and disinformation
    More education. Less misinformation.

    In this episode, Hari (University of Vienna), Katarzyna (University of Warsaw) and Jana (Charles University) discuss how social media, which many of us use daily, can mislead us when it comes to health-related information. The social media content that gets the most likes, shares and comments is often determined by algorithms, but this doesn't necessarily mean that the information is reliable. In reality, misinformation and disinformation tend to go viral more quickly than informative, evidence-based content. This can influence how individuals think of diseases, therapies, and even common health decisions in ways that may not be safe.

    They also talk about why it's so important to question what one sees online and to learn how to spot trustworthy information. The conversation also touches on vitamin D and antibiotic misuse, a growing problem driven by misinformation, and why taking antibiotics incorrectly can lead to serious resistance issues. Therefore, health literacy – the ability to distinguish between reliable sources and misleading claims – is crucial in protecting not just oneself, but entire communities from health challenges.

    By combining awareness, critical thinking, and improving our fact-checking skills, we can all play a role in slowing down the spread of harmful health misinformation.

    This podcast was produced by participants of the 'Central Workshop on Pharmacology Education and Misinformation', organised by the Central European Network for Teaching and Research in Academic Liaison (CENTRAL). This is a collaboration of researchers and educators from the University of Vienna (Austria), Charles University (Czech Republic) and the University of Warsaw (Poland).

    See Workshop news of 7 January 2026: CENTRAL Workshop on Pharmacology Education and Misinformation

    19 min
  • E18: Understanding sex-specific differences in alcohol use disorder (AUD)
    Does gender have any impact on prevention and treatment?

    Laureta Gashi shares her PhD project, which investigates Alcohol Use Disorder (AUD) from a sex-specific perspective. The conversation introduces AUD in accessible terms and explores how biological and physiological differences between males and females can influence addiction development, progression, and treatment outcomes. The discussion highlights the growing importance of incorporating sex-based analysis into addiction research, addressing historical gaps where such differences were often overlooked. Laureta also explores methodological considerations for investigating AUD, highlighting electrophysiology as a highly informative but labour- and time-intensive technique, and discusses common misconceptions related to alcohol dependence.

    Additionally, she shared her experience of being a PhaNuSpo student representative and the importance of this role in fostering collaboration and support among PhD students, as well as the personal and professional benefits of academic engagement.

    In summary, this episode provides scientific insight and a behind-the-scenes look at the life of a doctoral researcher, while also highlighting the intersection of science and student advocacy.

    Laureta’s latest publication on AUD:

    Gashi L, Khom S. Engagement of the Paraventricular Nucleus of the Thalamus During Withdrawal-Related Learning: Implications for Alcohol Use Disorder. Biological Psychiatry. In Biological Psychiatry Global Open Science. 2026 January, 6(1):100621. DOI: 10.1016/j.bpsgos.2025.100621.

    20 min
  • E17: Microbial drug resistance: the battle for effective antibiotics
    Mechanisms of resistance and challenges in drug development

    Why are bacteria evolving faster than our antibiotics?

    Antimicrobial resistance represents one of the most complex challenges at the intersection of microbiology, chemistry, and medicine. As bacteria rapidly evolve mechanisms to evade antibiotics, the pipeline for new anti-infective drugs struggles to keep pace.

    In this episode, our guest Micha, who is a PhD candidate in pharmaceutical science and part of the FWF-funded doc:fund Anti-Infectives Drug Discovery (AIDD) project team at the University of Vienna, takes a closer look specifically at Pseudomonas aeruginosa, a highly adaptable and resistant bacterium that exemplifies the difficulty of treating modern infections. We explore how resistance emerges, what multidrug resistance means at molecular level, and why features such as low membrane permeability, efflux pumps, and biofilm formation lead to frequent treatment failure.

    Additionally, we address the realities of novel anti-infective drug discovery such as why selectivity and toxicity are major hurdles, how permeability limits compound effectiveness, and why many drug candidates fail long before reaching patients.

    Beyond the science, the episode also highlights why early exposure to drug discovery matters for students and how creative, resilient thinking is essential for tackling antimicrobial resistance.

    19 min
  • E16: Nutrition for exercise recovery
    Impact of nutrition on exercise induced oxidative stress and recovery

    Markus, a PhD candidate in Sport Science at the University of Vienna, introduces in this podcast his newly developed high-intensity interval training (HIIT) model, designed to test how the body reacts to strenuous exercise under controlled conditions. We discussed what happens inside the body during high-intensity training, with particular attention on reactive oxygen species (ROS) production and physiological stress response mechanism. We also explored the powerful role of nutrition in shaping these responses, particularly the effect of polyphenol-rich foods and carbohydrate-rich foods in supporting recovery, reducing oxidative stress, and improving recovery outcomes.

    Additionally, this episode also explores the study’s design, including the rationale for recruiting healthy female adults and the practical challenges encountered during the data collection and research. Markus shares his key findings, and its future implications for nutritional and exercise-physiology research.
    Overall, this episode reflects on both the scientific and personal motivations behind the work, emphasising the value of understanding exercise-induced stress and how such insights can help both professional and hobby-athletes to train and improve their fitness more safely and effectively.

    Interested in his research? Then read more about Markus latest works:

    Gassner M, et al. Reactive oxygen species and IL-6 responses to resistance-based HIIT: A time-dependent analysis. Free Radic Biol Med. 2025. [doi: 10.1016/j.freeradbiomed.2025.10.272.]
    Gassner M, Bragagna L, Dasht Bayaz HH, Stumpf-Knaus C, Schlosser L, Lemberg J, Brem J, Pignitter M, Strauss M, Wagner K-H, et al. Acute Impact of Polyphenol-Rich vs. Carbohydrate-Rich Foods and Beverages on Exercise-Induced ROS and FRAP in Healthy Sedentary Female Adults—A Randomized Controlled Trial. Antioxidants. 2025; 14(12):1481. doi: 10.3390/antiox14121481

    26 min
  • E15: Behind the experiments
    Three PhD journeys

    Doing a PhD is often described as a journey - one filled with curiosity, persistence, and plenty of unexpected turns. In this episode, our team opens up about their personal PhD experiences: field of research, the motivation that sparked curiosity, managing different tasks and the small victories that kept them moving forward. You’ll hear their honest reflections and thoughtful conversations about what it really means to pursue PhD from their point of view. Whether you’re just starting your PhD, somewhere in the middle, or thinking about life after graduation, this episode offers a relatable experience to every early-career researcher.

    Podcast team: Hari Baskar Balasubramanian (PhD candidate) and Ranjith Kumar Ravi Kumar (postdoctoral researcher), both from the Department of Pharmaceutical Sciences, Anar Batzorig (PhD candidate), Department of Nutritional Sciences.

    Recording and editing: Anar Batzorig (PhD candidate), Department of Nutritional Sciences.

    30 min
  • E14: Proteomics - beyond the genome
    Unravelling the protein landscape

    Dr. Feng, a postdoctoral researcher in the Division of Pharmacology and Toxicology at the University of Vienna, starts the conversation by providing an overview of the Human Genome Project and explaining why it is essential to look beyond the genome to gain a comprehensive understanding of biology. With a clear passion for proteomics, he discusses advanced tools used to study proteins, focusing on the power of mass spectrometry. He highlights the latest developments in the field, including high-throughput techniques and the emerging role of single-cell proteomics in uncovering the complexity of systems such as the microbiome, as well as challenging samples like faeces and blood. He also illustrates the real-world impact of proteomics across multiple disciplines, including pharmaceutical and nutritional sciences, and shares everyday examples of how proteomic techniques can be used to profile food allergies. If you are fascinated by recent advancements and technical innovations in metaproteomics, don't miss this insightful conversation with Dr. Feng, who has over a decade of expertise in the field.

    Take a look at his recent article in Nature Communications:

    Xian, F., Brenek, M., Krisp, C. et al. Ultra-sensitive metaproteomics redefines the dark metaproteome, uncovering host-microbiome interactions and drug targets in intestinal diseases. Nat Commun 16, 6644 (2025).

    Guest: Feng Xian, postdoctoral researcher in the Division of Pharmacology and Toxicology at the University of Vienna.

    Hosts: Hari Baskar Balasubramanian (PhD candidate) and Ranjith Kumar Ravi Kumar (postdoctoral researcher), both from the Department of Pharmaceutical Sciences.
    Recording and editing: Anar Batzorig (PhD candidate), Department of Nutritional Sciences.

    27 min
  • E13: Musculoskeletal modelling
    Human movements in silico

    This episode offers an engaging introduction to the future of sport science: musculoskeletal modelling. It’s where the labs and computers come together to shape how we understand, train and care for the human body. Musculoskeletal modelling digitally recreates human movement, offering insights into forces and mechanics that are nearly impossible to capture through direct testing.

    In this conversation, Alexander explains how these models are built, what they can tell us, and why they matter. He discusses how researchers use data from a wide variety of cases, including artificial joint replacements, to train these models. He also addresses their limitations and the challenge of making them robust and reflective of real-life conditions.

    We explore practical applications such as:

    • Aufzählungs-Texthow joint contact force profiles can inform rehabilitation protocols to minimise joint loads,
    • Aufzählungs-Texthow athletes and coaches can optimise load progression and exercise selection,
    • Aufzählungs-Textand how insights from elite athletes may also apply to well-trained individuals or clinical populations aiming to build strength while preserving joint integrity.
    • The results show us that musculoskeletal modelling provides evidence-based tools that can guide safer rehabilitation, smarter and safer training and support long-term performance and musculoskeletal health.

      Curious? Then dive straight into Alexander’s podcast!

      Guest: Alexander Pürzel , PhD candidate at the Department of Sport and Human Movement Science.

      Hosts: Hari Baskar Balasubramanian (PhD candidate) and Ranjith Kumar Ravi Kumar (postdoctoral researcher), both from the Department of Pharmaceutical Sciences.
      Recording and editing: Anar Batzorig (PhD candidate), Department of Nutritional Sciences.

      30 min
    • E12: Impact of null results in a PhD
      Beyond the p-value: Why Null Findings Still Matter

      Null results are often overlooked in academic publishing, yet they play a critical role in advancing science with honesty and integrity.

      In this episode, we sit down with Marietta Zille, an Assistant Professor at the University of Vienna, to explore the impact of null findings during a PhD and how they can shape both research and researchers. Marietta shares her journey through the highs and lows of working with inconclusive data, which challenges the stigma often associated with "failed" experiments. We explore how embracing null results can foster scientific rigour, encourage transparency, and open unexpected career pathways. Marietta offers thoughtful reflections and practical advice for PhD students and early-career researchers navigating uncertainty in their work. Whether you are in the middle of writing your thesis or mentoring someone, this episode sheds light on the often-unspoken value of what doesn’t go as planned.

      Hosts: Hari Baskar Balasubramanian (PhD candidate) and Ranjith Kumar Ravi Kumar (postdoctoral fellow).

      Guest: Marietta Zille, Assistant Professor at Assistant Professor at the Division of Pharmacology and Toxicology, University of Vienna.
      Recording and editing: Anar Batzorig (PhD candidate)

      32 min
    • E11: Career perspective after a PhD
      Towards a fulfilling professional life.

      Making career choices can be exciting at the same time challenging. It is often a self-realisation process that promises fulfilment and professional growth.

      In this episode, we sit down with Daniel, who takes us through on his inspiring journey after earning a PhD that embodies his passion for academic research and teaching. Having spent several years as a professor at Anahuac University in Mexico, he transitioned to a postdoctoral research position in the Department of Pharmaceutical Sciences at the University of Vienna, bringing a unique perspective on navigating academic careers across borders. He shares offers practical advice for early-career researchers and PhD graduates considering their next steps, while weaving in personal stories that highlight resilience, growth, and the importance of keeping an open mind.
      Whether you’re planning your own post-PhD career or simply curious about the real-world experiences of academics, this conversation is full of insights you won’t want to miss.

      This episode was hosted and produced by Hari Baskar Balasubramanian (PhD candidate) and Ranjith Kumar Ravi Kumar (postdoctoral fellow), with Daniel Cuervo-Zanatta (postdoctoral fellow) as the guest. All are in the Department of Pharmaceutical Sciences. Anar Batzorig, a PhD candidate in the Department of Nutritional Sciences, recorded and edited it.

      28 min
    • E10: Research mobility as a PhD student
      Visiting another lab to learn and flourish

      Step into the world of international research with Bogi, a PhD student at the University of Pécs, as she recounts her three-month mobility experience at the University of Vienna.

      In this episode, Bogi offers a candid look at balancing productive research work with everyday life in a new country and environment. She shares how transitioning between institutions not only enhanced her professional skills and expanded her laboratory network, but also pushed her to leave her comfort zone, embrace new challenges and adapt to a different setting. Her journey is a powerful reminder that stepping away from the familiar can broaden both your academic network and your personal perspective.
      Tune in for an insightful conversation that might inspire you to embark on your own research mobility experience.

      22 min

    About LifeSciences ScienceLife

    From the publisher's feed

    Welcome to LifeSciences and ScienceLife, the podcast from the University of Vienna’s Doctoral School of Pharmaceutical, Nutritional, and Sport Sciences! Get ready to join our team of PhDs on a journey through current research topics and the PhD experience.