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Lights Along the Axoneme
This release contains only the music track from Base by Base Episode 298.
Song title: Lights Along the Axoneme
Original Base by Base episode: 298: Bi-allelic FSD1L variants in retinitis pigmentosa implicate photoreceptor axoneme
Original episode link: https://basebybase.com/episodes/fsd1l-retinitis-pigmentosa-axoneme
Article metadata:
Article title: Bi-allelic variants in FSD1L cause retinitis pigmentosa with or without neurological involvement
Journal: The American Journal of Human Genetics, Corrected proof. doi:10.1016/j.ajhg.2026.01.015
DOI: 10.1016/j.ajhg.2026.01.015
Reference: Lin S., Cancellieri F., Cao Y., et al. Bi-allelic variants in FSD1L cause retinitis pigmentosa with or without neurological involvement. The American Journal of Human Genetics 113, 1–11 (2026). https://doi.org/10.1016/j.ajhg.2026.01.015
Lyrics:
Verse 1
In the hush of bright screens, tiny filaments align
Silver threads that carry every scattered sign
A name like a whisper, FSD1L along the line
Tracing light through narrow halls where shadow meets design
Pre-Chorus
There was a gap in a pattern, a slit the eye can feel
An exon folded out of sight, a traffic rule made real
When the map forgets a doorway, signals drift and peel
Chorus
Follow the light along the axoneme, don't let it fade
We hold the missing pieces up until the dark unwinds
From shadow to a filament that finds its way home
We learn the language of the eye and teach the light to roam
Verse 2
Six faces in the pedigrees, a spectrum in their gaze
From steady dusk to restless nights, the retina keeps its ways
Isoforms like different passports, some lost at the gate
A quiet splice, a hidden cut that changes fate
Bridge
In the splice, a tiny deletion, exon ten-b erased
Cells reroute their luggage, outer segments left unlaced
But knowing where the pathway breaks is where the hope is traced
Final Chorus
So follow the light along the axoneme, it calls us on
We read the threads, we map the code until the morning comes
A filament restored, a signal strong enough to sing
Bring the lost exon back to the road — let every photon's voice bring morning
View all episodes
By Gustavo Barcelos BarraThis release contains only the music track from Base by Base Episode 298.
Song title: Lights Along the Axoneme
Original Base by Base episode: 298: Bi-allelic FSD1L variants in retinitis pigmentosa implicate photoreceptor axoneme
Original episode link: https://basebybase.com/episodes/fsd1l-retinitis-pigmentosa-axoneme
Article metadata:
Article title: Bi-allelic variants in FSD1L cause retinitis pigmentosa with or without neurological involvement
Journal: The American Journal of Human Genetics, Corrected proof. doi:10.1016/j.ajhg.2026.01.015
DOI: 10.1016/j.ajhg.2026.01.015
Reference: Lin S., Cancellieri F., Cao Y., et al. Bi-allelic variants in FSD1L cause retinitis pigmentosa with or without neurological involvement. The American Journal of Human Genetics 113, 1–11 (2026). https://doi.org/10.1016/j.ajhg.2026.01.015
Lyrics:
Verse 1
In the hush of bright screens, tiny filaments align
Silver threads that carry every scattered sign
A name like a whisper, FSD1L along the line
Tracing light through narrow halls where shadow meets design
Pre-Chorus
There was a gap in a pattern, a slit the eye can feel
An exon folded out of sight, a traffic rule made real
When the map forgets a doorway, signals drift and peel
Chorus
Follow the light along the axoneme, don't let it fade
We hold the missing pieces up until the dark unwinds
From shadow to a filament that finds its way home
We learn the language of the eye and teach the light to roam
Verse 2
Six faces in the pedigrees, a spectrum in their gaze
From steady dusk to restless nights, the retina keeps its ways
Isoforms like different passports, some lost at the gate
A quiet splice, a hidden cut that changes fate
Bridge
In the splice, a tiny deletion, exon ten-b erased
Cells reroute their luggage, outer segments left unlaced
But knowing where the pathway breaks is where the hope is traced
Final Chorus
So follow the light along the axoneme, it calls us on
We read the threads, we map the code until the morning comes
A filament restored, a signal strong enough to sing
Bring the lost exon back to the road — let every photon's voice bring morning