Dr. Selk interviews Dr. EJ Mayeaux, the chairman of the Department of Family and Preventative Medicine and professor of Obstetrics and Gynecology at the University of South Carolina, about lichen simplex chronicus (LSC). Topics covered include the definition of LSC, how common LSC is, diagnosis, what advice to give to patients, treatment options, counselling around steroid use, medications for controlling itch, recurrence rate, and the importance of motivating patients for cure.