In this episode, Dr. Faisal Rafiq describes the unmatched effectiveness of lithium as a mood stabilizer, highlighting its role in treating bipolar disorder and its unique status as one of the few naturally occurring psychiatric medications. He discusses key side effects—including the classic “peeing like a racehorse”—as well as important monitoring protocols, and the differences between extended-release and immediate-release formulations. A must-listen for clinicians seeking clarity on lithium’s powerful role in mood disorder management.