LockBit has redefined ransomware with modular payloads, rapid encryption, and precision targeting across Windows, Linux, ESXi, and even macOS. In this episode, we dissect the full LockBit kill chain, from initial access through double extortion, and break down a real 2025 case study of a $600K breach. More importantly, we share how security leaders and IT teams can operationalize defense using automation, risk-based patching, and real-time mitigation. Whether you’re a CISO or a security engineer, this is your strategic guide to stopping ransomware before it detonates.