The central message of this sermon is that following Jesus is what makes us great in the eyes of heaven, not our natural abilities or talents. The story of Peter and the fishermen being called by Jesus to leave their nets and follow him illustrates that willingness to surrender to God's calling and follow Him is the key to true greatness. This idea advances the belief that spiritual success and significance are more important than worldly achievements and accomplishments. The takeaway from this sermon is that we should prioritize following Jesus above all else, even if it means leaving behind our comfortable and familiar lives, just as Peter and the other fishermen did in this story.