M2 occlusions can present with serious neurological deficits, resulting in large infarcts and significant morbidity and mortality. The paper discussed in this podcast concludes that patients with M2 occlusions and higher baseline deficits (NIHSS score ≥9) may benefit from endovascular therapy, thus potentially expanding the category of acute ischemic strokes amenable to intervention.

Listen to the conversation between the Editor-in-Chief of JNIS, Felipe de Albuquerque, and Ansaar Rai (Department of Interventional Neuroradiology, West Virginia University Hospital, USA), who is the co-author of “A population-based incidence of M2 strokes indicates potential expansion of large vessel occlusions amenable to endovascular therapy”. Read the Editor’s Choice paper of June 2018 on the JNIS website: jnis.bmj.com/content/10/6/510.