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Magnesium supplements are marketed like different compounds with different biological targets - i.e., “for sleep,” “for the brain,” “for stress,” “for energy.” But the foundation of these claims depends on chemistry: how magnesium salts dissolve, how they release Mg²⁺ in the gut, and how much actually reaches circulation.
Part 1 breaks down the first half of the magnesium story: why magnesium must be paired with a counter-ion, how dissolution determines real absorption, and what modern data show when common salts like citrate, glycinate, and oxide are compared head-to-head.
The goal: separating marketing myths from measurable differences in solubility, acute bioavailability, and baseline magnesium status
00:00 Introduction to Magnesium Forms
00:30 Magnesium's Chemical Nature
01:11 Absorption Differences Among Magnesium Forms
01:35 Clinical Studies on Magnesium Absorption
04:24 Magnesium in Animal Studies
06:05 Human Studies on Magnesium
08:47 Conclusion and Preview of Part Two
By Dr. William WallaceMagnesium supplements are marketed like different compounds with different biological targets - i.e., “for sleep,” “for the brain,” “for stress,” “for energy.” But the foundation of these claims depends on chemistry: how magnesium salts dissolve, how they release Mg²⁺ in the gut, and how much actually reaches circulation.
Part 1 breaks down the first half of the magnesium story: why magnesium must be paired with a counter-ion, how dissolution determines real absorption, and what modern data show when common salts like citrate, glycinate, and oxide are compared head-to-head.
The goal: separating marketing myths from measurable differences in solubility, acute bioavailability, and baseline magnesium status
00:00 Introduction to Magnesium Forms
00:30 Magnesium's Chemical Nature
01:11 Absorption Differences Among Magnesium Forms
01:35 Clinical Studies on Magnesium Absorption
04:24 Magnesium in Animal Studies
06:05 Human Studies on Magnesium
08:47 Conclusion and Preview of Part Two