Magnesium salts are often marketed as if they target specific tissues - i.e., “threonate for the brain,” “glycinate for calm,” “taurate for the heart.” Part 2 breaks down what the evidence actually shows: animal studies demonstrating tissue differences that have never been replicated in humans, cognitive and sleep trials where multiple forms show benefit, and meta-analytic data indicating what really drives long-term outcomes.

The goal: clarify the real distinctions between magnesium forms, ligand effects, and dose requirements so listeners can understand what truly determines magnesium’s impact in humans.

00:00 Introduction to Magnesium Forms

00:22 Zooming Out: Broader Human Data

01:08 Systematic Reviews and Meta-Analyses

02:10 Key Findings on Magnesium Benefits

04:05 Understanding Magnesium Salts and Ligands

07:13 Practical Applications and Recommendations

09:32 Conclusion and Final Thoughts

• Doi: 10.1186/s40795-016-0121-3
• PMID: 11550076
• PMID: 31330811
• PMID: 39252819
• PMID: 26519439
• PMID: 34111673
• PMID: 23853635
• doi: 10.3390/nu9050429
• PMID: 39009081