Why are malaria vaccines so hard to make?

Lawrence Wang is an MD-DPhil candidate in vaccine research at Oxford, a medical school student at UC San Diego, and a NIH Oxford-Cambridge Scholar at National Institutes of Health (NIH) in the Intramural Research Program (IRP). In this 1hr+ session, Lawrence and I discuss everything from malaria vaccines to cytokine storms to benefits of doing an MD-PhD. He has written many articles on med school insider, has a public health paper out on the private sector drug shops and anti-malarials in Uganda, and fences foil on the Oxford blues fencing team. Tune in for an exciting session!

2:20 Malaria Vaccine and DPhil work

4:16 Monoclonal antibodies

8:53 How do you isolate antibodies?

13:02 £30,000 experiment - Berkeley Lights machine

23:23 Cytokine Storm!

35:53 Malaria vs Immune System

45:52 Current Malaria Vaccines

50:48 Chicken Pox and Dengue

51:42 Malaria trials on children

52:37 Scaling vaccine production

56:40 Recent thoughts on COVID-19 - other variants...

58:59 Benefit of doing an MD-PhD

1:01:05 Cost of £30,000 experiment - Berkeley Lights machine

1:02:14 Public health research on privately owned anti-malaria drug shops in Uganda - https://malariajournal.biomedcentral.com/articles/10.1186/s12936-018-2454-7

1:08:18 Perceptions of vaccines in rural Uganda

1:10:33 Malaria and economics - https://www.abpi.org.uk/value-and-access/vaccines/economic-and-societal-impacts-of-vaccines/

1:12:36 Med Insider Blogs

https://medschoolinsiders.com/author/lawrencewang/

1:15:21 Reflections on an MD-PhD

1:17:15 Year abroad at UCL - Infection and Immunity

1:21:31 Lawrence’s inspirations and role models - Bill Gates and Anthony Bourdain (Chef)

1:24:45 Fencing vs medical training + nutrition and injuries

1:36:37 Next steps

1:39:36 Where can people reach out to you?

[email protected]