Managed Care Cast

Managed Care Cast

By Managed Care CastScience
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Managed Care Cast episodes

  • No Caregiver, No Cure: Patty and Brian Koffman on Why Care Partners Are Critical to Cancer Therapy Access
    Caregivers are essential to cancer outcomes and access to newer therapies, but it is unclear whether resources will follow the evidence, according to husband and wife Brian Koffman, MDCM, and Patty Koffman, cofounders of the CLL Society. In this episode, recorded at the Patient-Centered Oncology Care conference, the couple reflect on the “No Caregiver, No Cure” panel that Patty participated in. They discuss research tying caregiver well-being to patient outcomes, the growing reliance on caregivers as chimeric antigen receptor T-cell therapy and bispecific antibodies move to the outpatient setting, and what pharma could do to support caregivers.
    Other resources:
    1. Caffrey M. The CAR T caregiver: “never in the limelight,” but critical to access. Am J Manag Care. 2026;32(Spec 5):SP180-SP182.
    2. Yang D, Troy JD, Branchaud B, Herring KW, El-Jawahri A, LeBlanc TW. "Longitudinal associations between patient and caregiver quality of life following hematopoietic stem cell transplantation." J Clin Oncol.2026;44(16_suppl):12087. doi:10.1200/jco.2026.44.16_suppl.12087
    3. Schwartz AJ, Riedel RF, LeBlanc TW, et al. The experiences of older caregivers of cancer patients following hospital discharge. Support Care Cancer. 2019;27(2):609-616. doi:10.1007/s00520-018-4355-2
    14 min
  • Closing the Gap: From Whole-Patient Care to Payer Data, What AON Is Doing for Patients Beyond the Clinic
    In part 2 of this conversation recorded at Patient-Centered Oncology Care 2026 in Nashville, Melody Chang, vice president of pharmacy operations at American Oncology Network (AON), talks with 2 AON colleagues. Susan Sabo Wagner, vice president of clinical innovation, explains why financial toxicity should be managed as a clinical toxicity. She also covers how electronic patient-reported outcomes can support patients on CAR T-cell and bispecific therapies between visits, and how AON is rolling out behavioral health partnerships, distress screening, and area deprivation index data across its practices. Alti Rahman, chief strategy and innovation officer, describes how AON is now supplying quality measures to payers instead of receiving them, and previews a closing panel on building trust among payers, providers, and patients through 2030. Both share what stood out most at the meeting, from patient access to keeping pace with fast-moving therapies.
    15 min
  • How Iberdomide and CELMoDs Are Transforming Relapsed Myeloma Care
    For years, first-relapse myeloma regimens have delivered just 1 to 2 years of progression-free survival and immunomodulatory drugs were dosed to the maximum tolerated dose. Iberdomide, the first CELMoD approved by the FDA and the first myeloma approval based on minimal residual disease negative status, changes this narrative. In this episode, we speak with Sagar Lonial, MD, FACP, FASCO, professor and chair of the Department of Hematology and Medical Oncology at Emory University School of Medicine, chief medical officer at Winship Cancer Institute, and lead investigator of the phase 3 EXCALIBER trial. Lonial breaks down the new EXCALIBER data he presented at IMS 2026, including MRD negativity rates for the study and comparator arms; how dosing was chosen for optimal fit rather than force; and and why MRD as an end point has potential to get new therapeutics to patients faster.
    18 min
  • Value-Based Oncology After the Enhancing Oncology Model
    Opaque benchmarks, payment lags of 12 to 18 months, and rules that changed mid-model led American Oncology Network (AON) to exit the Enhancing Oncology Model (EOM), according to AON Chief Medical Officer Stephen "Fred" Divers, MD.
    In this inaugural episode of The Business of Value, Divers tells host Lalan Wilfong, MD, chief medical officer of Navista, how 505(b)(2) drugs complicated practice finances, why retrospective data limited the ability to improve, and why other payers did not follow Medicare's lead. He also explains how AON is pursuing other value-based arrangements built on real-time data and what practices should know before joining similar models.
    30 min
  • Closing the Gap: How AON Is Turning AI and the Patient Voice Into Practice
    Community oncology practices can close the gap between innovation and implementation by building patient feedback into real-time clinical pathways, using AI to speed up physician decision-making, and better supporting caregivers of patients on CAR T and bispecific therapies, according to leaders from the American Oncology Network (AON).
    In the first of 2 podcasts from Patient-Centered Oncology Care 2026, Melody Chang, RPh, MBA, BCOP, is joined by Fred Divers, MD; Puneeth Indurlal, MD; and Brooke Peters, PharmD. They recap their PCOC panels and explain how the discussions connect to AON's work on clinical trials, rural access, and caregiver education.
    32 min

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