From narrow volume windows to SGLT2 inhibitors and emerging devices, Drs Kevin Alexander and Sarah Cuddy discuss heart failure care in ATTR-CM.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/ca8/p04/podcast-attr-cm-s1-ep4-2026a10006he. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Transthyretin-Related Amyloidosis https://emedicine.medscape.com/article/335301-overview

Diversity of Heart Failure Phenotypes in Transthyretin Amyloid Cardiomyopathy. More Than Just Heart Failure With Preserved Ejection Fraction https://pubmed.ncbi.nlm.nih.gov/39460551/

Transthyretin Amyloid Cardiomyopathy: The Plot Thickens as Novel Therapies Emerge https://pubmed.ncbi.nlm.nih.gov/41210313/

The Role of SGLT2-Inhibitors Across All Stages of Heart Failure and Mechanisms of Early Clinical Benefit: From Prevention to Advanced Heart Failure https://pubmed.ncbi.nlm.nih.gov/40149587/

Mineralocorticoid Receptor Antagonists in Heart Failure: An Update https://pubmed.ncbi.nlm.nih.gov/39584253/

Primary Systemic Amyloidosis https://emedicine.medscape.com/article/1093258-overview

Guideline-Directed Medical Therapy Intolerance in Heart Failure https://pubmed.ncbi.nlm.nih.gov/39466259/

Conventional Heart Failure Therapy in Cardiac ATTR Amyloidosis https://pubmed.ncbi.nlm.nih.gov/37216684/

Device Therapies for Heart Failure With Reduced Ejection Fraction: A New Era https://pubmed.ncbi.nlm.nih.gov/39494238/

CardioMEMS Heart Failure System: An Up-to-Date Review https://pubmed.ncbi.nlm.nih.gov/39991420/

Mechanisms of Chronotropic Incompetence in Heart Failure With Preserved Ejection Fraction https://pubmed.ncbi.nlm.nih.gov/32164435/

Cardiac Resynchronization Therapy https://www.ncbi.nlm.nih.gov/books/NBK567773/

Kidney Outcomes in Transthyretin Amyloid Cardiomyopathy https://pubmed.ncbi.nlm.nih.gov/39550765/

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