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Managing Sexual Side Effects of SSRI's - Considerations for Saffron and Probiotics
In this episode, Dr. Stephanie Bayliss, a Naturopathic Doctor based in British Columbia, reviews how we assess and manage sexual side effects from SSRI’s. Up to 80% of SSRI treated patients can experience sexual side effects. This may include changes to desire, arousal or satisfaction. Dr. Bayliss explores both the conventional care guidelines on managing these sexual side effects, and promising up and coming integrative solutions, including Saffron and Probiotics.
References:
Hashemi-Mohammadabad, N., Taghavi, S.-A., Lambert, N., Moshtaghi, R., Bazarganipour, F. & Sharifi, M. (2024). Adjuvant administration of probiotic effects on sexual function in depressant women undergoing SSRIs treatment: a double-blinded randomized controlled trial. BMC Psychiatry, 24(1), 44. https://doi.org/10.1186/s12888-023-05429-w
Izadi, S., Mohammad-Alizadeh-Charandabi, S., Yadollahi, P., & Mirghafourvand, M. (2024). Effect of vitamin E with and without saffron on the sexual function in women of reproductive age with sexual dysfunction: a randomized controlled trial. BMC women's health, 24(1), 143. https://doi.org/10.1186/s12905-024-02980-w
Kashani, L., Raisi, F., Saroukhani, S., Sohrabi, H., Modabbernia, A., Nasehi, A. A., Jamshidi, A., Ashrafi, M., Mansouri, P., Ghaeli, P., & Akhondzadeh, S. (2013). Saffron for treatment of fluoxetine-induced sexual dysfunction in women: randomized double-blind placebo-controlled study. Human psychopharmacology, 28(1), 54–60. https://doi.org/10.1002/hup.2282
Modabbernia, A., Sohrabi, H., Nasehi, A. A., Raisi, F., Saroukhani, S., Jamshidi, A., Tabrizi, M., Ashrafi, M., & Akhondzadeh, S. (2012). Effect of saffron on fluoxetine-induced sexual impairment in men: randomized double-blind placebo-controlled trial. Psychopharmacology, 223(4), 381–388. https://doi.org/10.1007/s00213-012-2729-6
Perlis, R. H., Laje, G., Smoller, J. W., Fava, M., Rush, A. J., & McMahon, F. J. (2009). Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 34(7), 1819–1828. https://doi.org/10.1038/npp.2009.4
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By Dr. Jordan Robertson NDIn this episode, Dr. Stephanie Bayliss, a Naturopathic Doctor based in British Columbia, reviews how we assess and manage sexual side effects from SSRI’s. Up to 80% of SSRI treated patients can experience sexual side effects. This may include changes to desire, arousal or satisfaction. Dr. Bayliss explores both the conventional care guidelines on managing these sexual side effects, and promising up and coming integrative solutions, including Saffron and Probiotics.
References:
Hashemi-Mohammadabad, N., Taghavi, S.-A., Lambert, N., Moshtaghi, R., Bazarganipour, F. & Sharifi, M. (2024). Adjuvant administration of probiotic effects on sexual function in depressant women undergoing SSRIs treatment: a double-blinded randomized controlled trial. BMC Psychiatry, 24(1), 44. https://doi.org/10.1186/s12888-023-05429-w
Izadi, S., Mohammad-Alizadeh-Charandabi, S., Yadollahi, P., & Mirghafourvand, M. (2024). Effect of vitamin E with and without saffron on the sexual function in women of reproductive age with sexual dysfunction: a randomized controlled trial. BMC women's health, 24(1), 143. https://doi.org/10.1186/s12905-024-02980-w
Kashani, L., Raisi, F., Saroukhani, S., Sohrabi, H., Modabbernia, A., Nasehi, A. A., Jamshidi, A., Ashrafi, M., Mansouri, P., Ghaeli, P., & Akhondzadeh, S. (2013). Saffron for treatment of fluoxetine-induced sexual dysfunction in women: randomized double-blind placebo-controlled study. Human psychopharmacology, 28(1), 54–60. https://doi.org/10.1002/hup.2282
Modabbernia, A., Sohrabi, H., Nasehi, A. A., Raisi, F., Saroukhani, S., Jamshidi, A., Tabrizi, M., Ashrafi, M., & Akhondzadeh, S. (2012). Effect of saffron on fluoxetine-induced sexual impairment in men: randomized double-blind placebo-controlled trial. Psychopharmacology, 223(4), 381–388. https://doi.org/10.1007/s00213-012-2729-6
Perlis, R. H., Laje, G., Smoller, J. W., Fava, M., Rush, A. J., & McMahon, F. J. (2009). Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 34(7), 1819–1828. https://doi.org/10.1038/npp.2009.4