I provide an extensive overview of the recent scientific review "Is a Mask That Covers the Mouth and Nose Free from Undesirable Side Effects in Everyday Use and Free of Potential Hazards" which was published on April 21, 2021 in the "International Journal of Environmental Research and Public Health." Topics are addressed from multiple disciplines and include: MIES-Mask Induced Exhaustion Syndrome, SBS-Sick Building Syndrome, HIF-Hypoxia Induced Factor, FM C02 Gradient (Fetal-Maternal), Metabolic Syndrome, voice disorders, decrease of empathy, and more. The connection of mask concerns to low oxygen and high carbon dioxide levels with anxiety and panic disorders and other pre-existing conditions are highlighted. Access the original study link here: https://www.mdpi.com/1078850