Master USMLE

Master USMLE: Fatigue, Back Pain, and Anemia – What Are You Missing?


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A patient presents with fatigue, back pain, and weight loss—common complaints that are easy to overlook. But when lab results show anemia, kidney dysfunction, and an unexpected electrolyte abnormality, the real concern becomes clear.

In this episode of Master USMLE, we break down a classic Step 2 CK case, focusing on:

  • Key clinical clues that point to a serious underlying condition
  • The most important lab findings you cannot ignore
  • Common mistakes students make when working up similar cases
  • How to differentiate this from other conditions with overlapping symptoms
  • The right tests to order and why imaging choice is critical

This is the case that many students get wrong—but after this episode, you won’t.

Stay sharp, study smart, and let’s master Step 2 CK together.

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Master USMLEBy Dr. Amin Afrasiabi