In this episode of Master USMLE, we break down a puzzling case of a patient with progressive confusion, headaches, and visual disturbances. The symptoms have developed over days to weeks, raising suspicion for a serious underlying condition often tested on the exam.

Is this an opportunistic infection? A demyelinating disease? A space-occupying lesion? We will walk through the key clinical findings, next best steps, and differential diagnoses before revealing the final answer.

Stay tuned as we think through the case like a test-taker, highlight high-yield concepts, and reinforce Step 2 CK strategies to help you score higher on exam day.