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Aspirin

Generic Name

Aspirin

Trade Name

Bayer Aspirin

Indication

rheumatoid arthritis, osteoarthritis, ischemic stroke and MI prophylaxis

Action

inhibits the production of prostaglandins which leads to a reduction of fever and inflammation, decreases platelet aggregation leading to a decrease in ischemic diseases

Therapeutic Class

antipyretics, non-opioid, analgesics

Pharmacologic Class

salicylates

Nursing Considerations

use caution in bleeding disorders, chronic alcohol use

may lead to Stevens-Johnson syndrome, laryngeal edema, and anaphylaxis

increases risk for bleeding with warfarin, heparin, and clopidogrel

increased risk for GI bleeding with NSAID use

monitor liver function tests

concurrent use with alcohol may increase risk for GI bleeding