Captopril

Generic Name

captopril

Trade Name

Capoten

Indication

hypertension, management of CHF, decrease progression of DM neuropathy

Action

block conversion of angiotensin I to angiotensin II, increases renin levels and decreases aldosterone leading to vasodilation

Therapeutic Class

antihypertensives

Pharmacologic Class

ACE Inhibitor

Nursing Considerations

can cause neutropenia - check WBCs regularly

use cautiously with potassium supplements and potassium sparing diuretics.

use cautiously with diuretic therapy

administer 1 hour before meals

monitor blood pressure often

monitor weight and fluid status

monitor renal profile

monitor CBC frequently

May lead to Rhabdomyolysis

Dry cough