Clopidogrel

Generic Name

clopidogrel

Trade Name

Plavix

Indication

atherosclerotic events, MI, CVA, PVD, acute coronary syndrome

Action

inhibits platelet aggregation

Therapeutic Class

Antiplatelet agent

Pharmacologic Class

platelet aggregation inhibitors

Nursing Considerations

may cause GI bleeding, neutropenia, hypercholesterolemia

may increase risk for bleeding in warfarin, aspirin, heparin

can increase risk for bleeding with garlic, ginkgo, ginger

monitor for signs of bleeding

monitor bleeding times

monitor CBS and platelet count

discontinue use 5-7 days before surgery