Divalproex (valproic acid derivative)

Generic Name

divalproex

Trade Name

Depakote

Indication

seizures, manic episodes, prevention of headache

Action

increases the level of GABA in CNS

Therapeutic Class

Anticonvulsant, vascular headache suppressants

Pharmacologic Class

none

Nursing Considerations

may cause suicidal thoughts, agitation, dizziness, insomnia, hepatotoxicity, pancreatitis

increases risk for bleeding with Warfarin

use caution with MAOIs

monitor liver function tests