Dr Feldman is joined by Drs Luke Johnson and Michelle Tarbox of the popular podcast Dermasphere, to discuss trends and hot topics in psoriasis.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002114. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Dermasphere - The Derm Podcast https://dermaspherepodcast.com/

Skincast https://healthcare.utah.edu/dermatology/skincast

Bimekizumab in Patients With Psoriatic Arthritis, Naive to Biologic Treatment: A Randomised, Double-Blind, Placebo-Controlled, Phase 3 Trial (BE OPTIMAL) https://pubmed.ncbi.nlm.nih.gov/36493791/

Inflammatory Bowel Disease Induced by Bimekizumab https://pubmed.ncbi.nlm.nih.gov/35664026/

Short-Term Exposure to a Western Diet Induces Psoriasiform Dermatitis by Promoting Accumulation of IL-17A-Producing γδ T Cells https://pubmed.ncbi.nlm.nih.gov/32057839/

Dietary Intervention and Supplements in the Management of Psoriasis: Current Perspectives https://pubmed.ncbi.nlm.nih.gov/35769285/

The Patient's Guide to Psoriasis Treatment. Part 4: Goeckerman Therapy https://pubmed.ncbi.nlm.nih.gov/27474032/

Deucravacitinib Versus Placebo and Apremilast in Moderate to Severe Plaque Psoriasis: Efficacy and Safety Results From the 52-Week, Randomized, Double-Blinded, Placebo-Controlled Phase 3 POETYK PSO-1 Trial https://pubmed.ncbi.nlm.nih.gov/35820547/

Emerging Oral Therapies for the Treatment of Psoriasis: A Review of Pipeline Agents https://pubmed.ncbi.nlm.nih.gov/38258121/

Callus and Its Keratin Before and After Treatment With Acid Sodium Thioglycolate. A Study by Scanning and Conventional Electron Microscopy https://pubmed.ncbi.nlm.nih.gov/5132158/

 Join Drs Steven Feldman and John Koo as they discuss psychodermatology and the link between psoriasis, anxiety, depression, and other mental health conditions.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002113. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Psoriasis https://emedicine.medscape.com/article/1943419-overview

Management of Psychodermatologic Disorders https://www.medscape.com/viewarticle/730033_5

Association Between Psoriasis and Depression: A Traditional Review https://pubmed.ncbi.nlm.nih.gov/32944430/

The Role of Interleukin 23/17 Axis in Psoriasis Management: A Comprehensive Review of Clinical Trials https://pubmed.ncbi.nlm.nih.gov/38616886/

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis https://pubmed.ncbi.nlm.nih.gov/23892536/

Biologic Treatments of Psoriasis: An Update for the Clinician https://pubmed.ncbi.nlm.nih.gov/33623366/

Role of Janus Kinase Inhibitors in Therapy of Psoriasis https://pubmed.ncbi.nlm.nih.gov/34640327/

Biologic Treatment Algorithms for Moderate-to-Severe Psoriasis With Comorbid Conditions and Special Populations: A Review https://pubmed.ncbi.nlm.nih.gov/33861409/

Depression and Suicidality in Psoriasis and Clinical Studies of Brodalumab: A Narrative Review https://pubmed.ncbi.nlm.nih.gov/31939925/

Use of the Patient Health Questionnaire (PHQ-9) in Practice: Interactions Between Patients and Physicians https://pubmed.ncbi.nlm.nih.gov/32564676/

Join Drs Steven Feldman and Robert Kushner as they discuss the role of dermatologists in treating obesity in conjunction with psoriasis.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002112. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Psoriasis https://emedicine.medscape.com/article/1943419-overview

Medscape InDiscussion: Obesity https://www.medscape.com/viewarticle/982631

Update on Obesity in Psoriasis Patients https://pubmed.ncbi.nlm.nih.gov/37895330/

Obesity and Severe Obesity Prevalence in Adults: United States, August 2021-August 2023 https://www.cdc.gov/nchs/data/databriefs/db508.pdf

Obesity-Related Complications, Healthcare Resource Use and Weight Loss Strategies in Six European Countries: The RESOURCE Survey https://pubmed.ncbi.nlm.nih.gov/37258646/

The Link Between Obesity and the Skin https://pubmed.ncbi.nlm.nih.gov/35369048/

Acanthosis Nigricans https://emedicine.medscape.com/article/1102488-overview

Medications for Obesity: A Review https://pubmed.ncbi.nlm.nih.gov/39037780/

The Role of Interleukin 23/17 Axis in Psoriasis Management: A Comprehensive Review of Clinical Trials https://pubmed.ncbi.nlm.nih.gov/38616886/

Role of the Gut-Brain Axis in Energy and Glucose Metabolism https://pubmed.ncbi.nlm.nih.gov/35474341/

Hidradenitis Suppurativa https://emedicine.medscape.com/article/1073117-overview

Biomarkers of Inflammation in Obesity-Psoriatic Patients https://pubmed.ncbi.nlm.nih.gov/31275060/

Robert Kushner, MD https://drrobertkushner.com/

Join Drs Steven Feldman and Jules Lipoff as they discuss teledermatology, the cost of prescriptions, and other barriers to care people with psoriasis face.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002111. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

The Role of the Physician in Patient Perceptions of Barriers to Primary Adherence With Acne Medications https://pubmed.ncbi.nlm.nih.gov/29490358/

Ciclopirox Nail Lacquer Topical Solution 8% in the Treatment of Toenail Onychomycosis https://pubmed.ncbi.nlm.nih.gov/11051136/

Efinaconazole in Onychomycosis https://pubmed.ncbi.nlm.nih.gov/34902110/

Cost Effectiveness of Oral Terbinafine (Lamisil) Compared With Oral Fluconazole (Diflucan) in the Treatment of Patients With Toenail Onychomycosis https://pubmed.ncbi.nlm.nih.gov/11994041/

Prescription Cost-Saving Platforms in Dermatology https://pubmed.ncbi.nlm.nih.gov/39259524/

GoodRx https://www.goodrx.com

Mark Cuban CostPlus Drug Company https://www.costplusdrugs.com/

Drs Steve Feldman and Megan Noe fill in the gaps about pustular psoriasis, a relatively rare but serious condition that can be tough to diagnose.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986155). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Palmoplantar Pustulosis: Current Understanding of Disease Definition and Pathomechanism https://pubmed.ncbi.nlm.nih.gov/32201085/

Evaluation of a Case Series of Patients With Generalized Pustular Psoriasis in the United States https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655659/

Pathophysiology of Generalized Pustular Psoriasis https://pubmed.ncbi.nlm.nih.gov/36779688/

Trial of Spesolimab for Generalized Pustular Psoriasis https://pubmed.ncbi.nlm.nih.gov/34936739/

Drs Steve Feldman and Andrew Blauvelt have a fascinating chat about contrasts and similarities between biologics and biosimilars, covering pharmacoeconomic and legal differences between the US and Europe.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986154). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Biosimilar Drugs for Psoriasis: Principles, Present, and Near Future https://pubmed.ncbi.nlm.nih.gov/29549597/

International Psoriasis Council https://psoriasiscouncil.org/

Biosimilars for Psoriasis: Clinical Studies to Determine Similarity https://pubmed.ncbi.nlm.nih.gov/27639072/

Safety, Efficacy and Drug Survival of Biologics and Biosimilars for Moderate-to-severe Plaque Psoriasis https://pubmed.ncbi.nlm.nih.gov/29094341/

Dr Steven R. Feldman and nurse practitioner Lakshi M. Aldredge discuss systemic therapy for psoriasis and how nurse practitioners and physician associates fill an important gap.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986153). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199465/?report=reader

Tumor Necrosis Factor Inhibitors https://www.ncbi.nlm.nih.gov/books/NBK482425/

Deucravacitinib for the Treatment of Psoriatic Disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372960/

Drs Steven R. Feldman and Kim A. Papp discuss the expanding universe of opportunities and advances for halting limited psoriasis.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986152). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Trial of Roflumilast Cream for Chronic Plaque Psoriasis https://pubmed.ncbi.nlm.nih.gov/32668113/

Psoriasis in Special Localizations https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330687/

Vitamin D Analogs in the Treatment of Psoriasis: Where Are We Standing and Where Will We Be Going? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219168/

Dr Steve Feldman speaks with Drs Mehta, Ritchlin, and Fried who share an exciting new roadmap for calming key psoriasis comorbidities.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986151). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Treatment of Psoriasis With Biologic Therapy Is Associated With Improvement of Coronary Artery Plaque Lipid-rich Necrotic Core: Results From a Prospective, Observational Study https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.120.011199

Treating the Skin With Biologics in Patients With Psoriasis Decreases the Incidence of Psoriatic Arthritis https://pubmed.ncbi.nlm.nih.gov/34281904/

The Patient Health Questionnaire-2: Validity of a Two-Item Depression Screener https://pubmed.ncbi.nlm.nih.gov/14583691/

Dr Steven Feldman and Leah Howard, National Psoriasis Foundation President and CEO, discuss how an unseen and unheard patient population has begun to step out and speak up — at the US Capitol and beyond.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986130). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

National Psoriasis Foundation (NPF) https://www.psoriasis.org/

Management of Psoriasis as a Systemic Disease: What Is the Evidence? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187293/

Psoriasis: Classical and Emerging Comorbidities https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323693/