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Mefloquine, the one with the black box warning
Edit: I'm not sure if Peace Corps is using Lariam. Many have said PC stopped using it, and at least some PCVs have stated there is a generic brand of mefloquine. The US has stopped selling Lariam in the US. If anyone has a relaible source of the PC's use of Lariam, please share it with me and I'll update the episode.
For further information:
Tan KR, Magill AJ, Parise ME, Arguin PM; Centers for Disease Control and Prevention. Doxycycline for malaria chemoprophylaxis and treatment: report from the CDC expert meeting on malaria chemoprophylaxis. Am J Trop Med Hyg. 2011 Apr;84(4):517-31. doi: 10.4269/ajtmh.2011.10-0285. PMID: 21460003; PMCID: PMC3062442.
National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Committee to Review Long-Term Health Effects of Antimalarial Drugs; Board on Population Health and Public Health Practice; Styka AN, Savitz DA, editors. Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis. Washington (DC): National Academies Press (US); 2020 Feb 25. 4, Mefloquine. Available from: https://www.ncbi.nlm.nih.gov/books/NBK556592/
Nevin RL, Ritchie EC. FDA Black Box, VA Red Ink? A Successful Service-Connected Disability Claim for Chronic Neuropsychiatric Adverse Effects From Mefloquine. Fed Pract. 2016 Oct;33(10):20-24. PMID: 30766139; PMCID: PMC6373714. Available from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373714/
Tan KR, Henderson SJ, Williamson J, Ferguson RW, Wilkinson TM, Jung P, Arguin PM. Long term health outcomes among Returned Peace Corps Volunteers after malaria prophylaxis, 1995-2014. Travel Med Infect Dis. 2017 May-Jun;17:50-55. doi: 10.1016/j.tmaid.2017.05.003. Epub 2017 May 6. PMID: 28487213.
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By Moz 15Edit: I'm not sure if Peace Corps is using Lariam. Many have said PC stopped using it, and at least some PCVs have stated there is a generic brand of mefloquine. The US has stopped selling Lariam in the US. If anyone has a relaible source of the PC's use of Lariam, please share it with me and I'll update the episode.
For further information:
Tan KR, Magill AJ, Parise ME, Arguin PM; Centers for Disease Control and Prevention. Doxycycline for malaria chemoprophylaxis and treatment: report from the CDC expert meeting on malaria chemoprophylaxis. Am J Trop Med Hyg. 2011 Apr;84(4):517-31. doi: 10.4269/ajtmh.2011.10-0285. PMID: 21460003; PMCID: PMC3062442.
National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Committee to Review Long-Term Health Effects of Antimalarial Drugs; Board on Population Health and Public Health Practice; Styka AN, Savitz DA, editors. Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis. Washington (DC): National Academies Press (US); 2020 Feb 25. 4, Mefloquine. Available from: https://www.ncbi.nlm.nih.gov/books/NBK556592/
Nevin RL, Ritchie EC. FDA Black Box, VA Red Ink? A Successful Service-Connected Disability Claim for Chronic Neuropsychiatric Adverse Effects From Mefloquine. Fed Pract. 2016 Oct;33(10):20-24. PMID: 30766139; PMCID: PMC6373714. Available from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373714/
Tan KR, Henderson SJ, Williamson J, Ferguson RW, Wilkinson TM, Jung P, Arguin PM. Long term health outcomes among Returned Peace Corps Volunteers after malaria prophylaxis, 1995-2014. Travel Med Infect Dis. 2017 May-Jun;17:50-55. doi: 10.1016/j.tmaid.2017.05.003. Epub 2017 May 6. PMID: 28487213.