In this episode, Urology Times Managing Editor Ben Saylor spoke with Elizabeth Hisle-Gorman, MSW, PhD, and David A. Klein, MD, MPH. They discuss the mental health patterns in transgender and gender-diverse youth and how they are affected by gender-affirming care. Hisle-Gorman is an associate professor of pediatrics and Klein is an associate professor of family medicine and pediatrics at Uniformed Services University, Bethesda, Maryland.