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meperidine
Trade NameDemerol
Indicationmoderate to severe pain, sedation
ActionBinds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS.
Therapeutic ClassOpioid Analgesic
Pharmacologic Classopioid agonists
Nursing Considerations• may cause alterations in mentation, hypotension, constipation, nausea, vomiting • assess BP, pulse, and respiratory rate prior to administration and frequently during administration • use caution if patient is receiving MAOIs • Narcan (naloxone) is the antidote for opioid agonists • can cause seizure • may increase pancreatic enzyme levels • assess bowel function
By Jon Haws, RN CCRN Alumnus4.4
158158 ratings
meperidine
Trade NameDemerol
Indicationmoderate to severe pain, sedation
ActionBinds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS.
Therapeutic ClassOpioid Analgesic
Pharmacologic Classopioid agonists
Nursing Considerations• may cause alterations in mentation, hypotension, constipation, nausea, vomiting • assess BP, pulse, and respiratory rate prior to administration and frequently during administration • use caution if patient is receiving MAOIs • Narcan (naloxone) is the antidote for opioid agonists • can cause seizure • may increase pancreatic enzyme levels • assess bowel function

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