HealthTech Deep Dive

MetaEdit Technology “Rewrites Gut Microbiota On-Site” Published in Science. A Future Where Black Boxes Are Structured and Intervened in Real Time!?


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This podcast episode describes two distinct topics, with the primary focus on a breakthrough in microbiome science involving a new gene-editing technology called MetaEdit. This technology, announced in Science magazine, allows for the direct genetic modification of gut bacteria within the body, overcoming the limitations of previous methods that required ex vivo manipulation of culturable bacteria. MetaEdit uses E. coli as a donor to deliver gene-editing tools, enabling the on-the-fly rewriting of the bacterial DNA and suggesting a future where scientists can structure the gut's "black box" and control microbial composition via diet. A much shorter, secondary source also details a development in medical administrative efficiency, announcing that the company GENOVA has launched a "multi-patient card" system utilizing transit IC cards to simplify patient registration at clinics.

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HealthTech Deep DiveBy Kazutaka Yoshinaga