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Michael Houghton’s discovery of the Hepatitis C virus in 1989 — along with colleagues Qui-Lim Choo and George Kuo — led to blood screening tests that have protected tens of millions of people from contracting the disease. In this podcast, Houghton — Canada Excellence Research Chair in Virology at the University of Alberta — discusses the scope of Hep C infection worldwide, describes his discovery of the virus and explains his current search for a vaccine that will help the World Health Organization reach its goal of eradicating Hep C by 2030.