Behind the Breakthroughs

Michelle Werner: Engineered tRNAs Offer Universal Solutions to Stop Codon Diseases


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When Michelle Werner, PhD, learned her son Caffrey had Duchenne muscular dystrophy, she left big pharma to lead Alltrna—a Flagship Pioneering company engineering tRNAs to tackle rare diseases with no treatments. On Behind the Breakthroughs, Werner shares her journey as both mother and CEO, and how Alltrna’s approach could unlock therapies for thousands of conditions caused by nonsense mutations.


Produced and hosted by Jonathan D. Grinstein, PhD


Audio mixed and mastered by David Mosely


Brought to you by Inside Precision Medicine (SAGE Publishing)

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Behind the BreakthroughsBy Inside Precision Medicine