Dr. Howard Smith Reports

Microfluidic Test System Allows Multi-Organ Testing


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Vidcast:  https://www.instagram.com/p/CzUNZXCxzeV/


A literal “body on a chip” permits the testing of drugs and other biologics on multiple organs simultaneously.  Developed at Northwestern University, the so-called Lattice device permits the simultaneous testing of potential therapeutics on up to 8 different organ systems.  The organ tissue samples or artificially-generated organoids are placed in separate wells, and the medications to be tested flow into each well via micro-channels.  Another function of Lattice permits testing the effects of one organ on another or others.  For example, a hormone-producing organ in one well is bathed in nutrient media that picks up the hormones and carries them to other wells containing other organs.  It’s a brave new world, and it’s coming……Someday soon.


https://pubs.rsc.org/en/Content/ArticleLanding/2023/LC/D3LC00378G


#microfluidics #organoids #drugtesting #lattice



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Dr. Howard Smith ReportsBy Howard G. Smith MD, AM