Feature Summary of iCCA in Keywords:
- Small duct iCCA: Mass forming. mucin-poor. CRP positive. BAP1, IDH1/2 mutation, and FGFR2 fusion.
- Large duct iCCA: geographic infiltrative. mucin-producing columnar epithelium. S100P-positive. Mutations in K -ras and SMAD4.
- Cholangioblastic cholangiocarcinoma: Women. young age. neuroendocrine-like cytology. inhinbin-positive. and NIPBL-NACC1 gene fusion.