The shiur focused on discussing the concept of nullification in mixtures, particularly in relation to holy foods such as Teruma, Orlah, and Klei Hakarem. Yitzie explained that these foods become nullified in a mixture of 101 parts, meaning that one part of holy food is nullified by 100 parts of ordinary food. They also discussed how Orlah and Klei Hakarem require a mixture of 200 parts of ordinary food to nullify one part of holy food, due to stricter prohibitions. The group explored various scenarios where holy foods mix with ordinary foods, considering factors such as flavor and the size of the mixture. 

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