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In this episode of Innovate and React we look at the interface between biology and chemistry. Alexandra, a biochemist studying mitochondrial biogenesis, shares her journey from moving to Germany, and ultimately diving into biochemistry. The conversation delves into the complex processes of mitochondrial function, including their role in energy production, calcium signaling, and apoptosis (programmed cell death). Alexandra discusses her current research on the ER SURF pathway and its implications for understanding protein transport, which could potentially lead to breakthroughs in treating diseases like cancer and Parkinson’s. The episode emphasizes the interconnectedness of chemistry and biology and the importance of fundamental research in advancing scientific knowledge.

00:46 Journey into Biochemistry

02:21 The Universal Language of Science

06:08 Understanding Mitochondria

12:10 Protein Transport in Cells

25:44 Understanding Protein Targeting in Mitochondria

28:17 Exploring the ER SURF Pathway

32:32 Research Methods and Yeast Cultures

48:34 Potential Applications and Future Implications

To hear more from Alexandra and other scientists talking about their PhD experience check out her podcast: Spotify, Apple Podcasts or Instagram!

If you would like to share your research in the podcast or have and interesting topic, comment, connect with me on LinkedIn or send me an email to [email protected]. Also let me know if you think PhD is worth it and why.

Many thanks to aloc for providing the music.