These video briefs feature expert insights on the latest clinical data presented at ACC 2025. Leading cardiologists discuss emerging nonsteroidal mineralocorticoid receptor antagonists (MRAs), their efficacy in heart failure management, and their potential advantages over traditional steroidal MRAs. The series explores key trial findings, safety considerations, and clinical implications for optimizing patient care. Viewers will gain practical knowledge on integrating these novel therapies into clinical practice to improve patient outcomes.