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We discuss the clinical features on the basis of a case series from the U.K. and then have a Q&A with pox virologist and UpToDate author on the topic, Dr. Stuart Isaacs.

Discussant: Stuart N. Isaacs, MD; Perelman School of Medicine at the University of Pennsylvania

Host: Benjamin P. Geisler, MD MPH

Recording date: May 30, 2022

0:00 Intro

1:09 Outline and Study Type

2:13 Background

5:31 Case Series

11:39 Q&A w/ Dr. Isaacs

References:

-Case series: Adler H et al. Lancet ID online early doi: 10.1016/S1473-3099(22)00228-6

-Comparison to Covid-19 case report/series: Rothe C et al N Engl J Med. 382(10); 970-1 doi: 10.1056/NEJMc2001468 https://pubmed.ncbi.nlm.nih.gov/32003551/

-Dr. Isaac’s UpToDate article: https://www.uptodate.com/contents/monkeypox

-Microbe.TV: This Week in Virology (TWiV) Special: Monkeypox clinical update with Dr. Daniel Griffin https://www.youtube.com/watch?v=dMiT73ycw-I

-Program for Monitoring Emerging Diseases (ProMED) Monkeypox update (06), 30 May 2022: https://promedmail.org/

-Centre for Infectious Disease Research and Policy (CIDRAP): WHO says monkeypox containable, but nations should be on alert. https://www.cidrap.umn.edu/news-perspective/2022/05/who-says-monkeypox-containable-nations-should-be-alert

-Phylogenetic trees: Hendrickson RC et al. Viruses 2010(2); 1933-67. doi: 10.3201/eid2409.171283 https://pubmed.ncbi.nlm.nih.gov/30124195/

-Virion schematics: ViralZone, from https://commons.wikimedia.org/wiki/File:Poxprot.jpg

-Discussion of on-going MPXV genome sequencing: https://virological.org/t/discussion-of-on-going-mpxv-genome-sequencing/802

-Genomic epidemiology of monkeypox virus: https://nextstrain.org/monkeypox?l=clock

#monkeypox #virus

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