Vincent, Elio and Michael recorded this episode of This Week in Microbiology before an audience at the 2013 General Meeting of the American Society for Microbiology in Denver, Colorado, where they spoke with Andrew Camilli, Ferric Fang, Suzanne Fleiszig, and Michelle Swanson about their research on a phage system for evading innate immunity, retractions of research papers, bacterial infections of the eye, and cytoplasmic defenses against intracellular bacteria.