Jehovah Mekodesh means 'the Lord who sanctifies,' revealing God's desire to make us holy. Holiness involves being set apart from sin and set apart to God. While justification happens at salvation, sanctification is a daily process of becoming more like Christ. We cannot achieve holiness on our own—it's God who sanctifies us through and through. The benefits of being set apart for God include full access to His presence, participation in His divine nature, and escape from worldly corruption. True holiness isn't just about avoiding sin but about being transformed by God's character.