This podcast outlines how we can better assess and respond to complex climate change risks. It highlights how multiple drivers of risk interact and how various risks can compound or cascade. Existing assessment frameworks often fail to fully account for these interactions. Three categories of increasing complexity are discussed: interactions among single drivers, interactions of multiple drivers within risk determinants (hazard, vulnerability, exposure, and response), and interactions among multiple distinct risks. Integrating responses to climate change as a determinant of risk is crucial for more informed decision-making and effective interventions.