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Neonatal Jaundice
Physiology RBC hemoglobin breakdown -> unconjugated (indirect) bilirubin Unconjugated (indirect) bilirubin -> liver -> conjugated (direct) bilirubin Conjugated (direct) bilirubin -> Eliminated in stool Causes of Hyperbilirubinemia Increased RBC turnover Sepsis Rh incompatibility RBC disorders Maternal diabetes Scalp hematoma Decreased/slow conjugation by the liver Peaks around day 5 of life Congenital liver disorders Gilbert/Crigler Najjar […]
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By Zack Olson, MD ; Mike Estephan, MD ; Maddie Watts, MDPhysiology RBC hemoglobin breakdown -> unconjugated (indirect) bilirubin Unconjugated (indirect) bilirubin -> liver -> conjugated (direct) bilirubin Conjugated (direct) bilirubin -> Eliminated in stool Causes of Hyperbilirubinemia Increased RBC turnover Sepsis Rh incompatibility RBC disorders Maternal diabetes Scalp hematoma Decreased/slow conjugation by the liver Peaks around day 5 of life Congenital liver disorders Gilbert/Crigler Najjar […]