In this episode, we delve into strategies to mitigate the risk of infection associated with external ventricular drains. We review the systematic review and meta-analysis titled "Is there a way to reduce the infection associated with external ventricular shunts? A systematic review and meta-analysis of the recent bundle of care," published in Neurosurgical Review in 2026. The study synthesizes evidence from various settings to identify effective bundles of care. Key findings highlight specific interventions that significantly reduce EVD-related infections, offering actionable insights for neurocritical care teams. Understanding these evidence-based practices is crucial for improving patient outcomes and patient safety. This podcast is for informational purposes only and does not constitute medical advice.