Magnesium sulfate is widely recommended for neuroprotection in pregnancies at risk of preterm delivery. However, the optimal gestational age for use is unclear. JAMA Associate Editor Melissa Simon, MD, MPH, and Caroline Crowther, MD, Liggins Institute, University of Auckland, discuss the use of magnesium sulfate at different gestational ages and potential benefit vs harms as reflected in the MAGENTA Trial.  Related Content:  Prenatal Intravenous Magnesium at 30-34 Weeks’ Gestation and Neurodevelopmental Outcomes in Offspring 

Neurodevelopmental Effects of Antenatal IV Magnesium Sulfate Between 30-34 Weeks' Gestation

Interviews with leading researchers and thinkers in health care about practice-changing research, innovations, and the most pressing issues facing medicine and health care today from JAMA, the Journal of the American Medical Association.

Medicine

Science & Medicine

Science

Health & Fitness

When initial treatment with varenicline or nicotine replacement doesn't work, does increasing dosage improve smoking cessation rates? Paul Cinciripini, PhD, of MD Anderson Cancer Center's Department of Behavioral Science, joins JAMA Executive Editor Gregory Curfman, MD, to discuss guidance on the best strategies for smoking cessation following an initial quit attempt.  Related Content:  Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement 

Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement

Extensive evidence documents health disparities for lesbian, gay, and bisexual (LGB) women, including worse physical, mental, and behavioral health than heterosexual women. Sarah McKetta, ScM, MD, PhD, discusses these factors and their link to premature mortality with JAMA Deputy Editor Linda Brubaker, MD, MS.  Related Content:  Disparities in Mortality by Sexual Orientation in a Large, Prospective Cohort of Female Nurses 

Examining Mortality Disparities by Sexual Orientation Among Female Nurses

Can real-time EHR–generated recommendations safely reduce antibiotic use in hospitalized patients with pneumonia or UTI? Shruti K. Gohil, MD, MPH, of the University of California-Irvine, joins JAMA Deputy Editor Preeti Malani, MD, MSJ, to discuss the INSPIRE randomized clinical trial.  Related Content:  Stewardship Prompts to Improve Antibiotic Selection for Pneumonia Stewardship Prompts to Improve Antibiotic Selection for Urinary Tract Infection Harnessing the Electronic Health Record to Improve Empiric Antibiotic Prescribing 

Stewardship Prompts to Improve Antibiotic Selection for Pneumonia and Urinary Tract Infection

Climate action is an urgent public health imperative. Climate change is causing excess morbidity and mortality and posing an increasing threat to mental health and well-being. The US health care sector is a significant contributor to this problem. A. Eugene Washington, MD, of Duke University, discusses accelerating climate action with JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.  Related Content:  Accelerating Climate Action Through Academic Health Systems 

Advancing Climate Action Through Academic Health Systems

The utility of prostate-specific antigen (PSA) screening for prostate cancer detection is impacted by detection of cancers with low risk of mortality. Editorialist Jeffrey J. Tosoian, MD, MPH, discusses a pragmatic approach to prostate cancer screening with JAMA Deputy Editor Mary L. (Nora) Disis, MD.  Related Content:  A Pragmatic Approach to Prostate Cancer Screening Prostate Cancer Screening With PSA, Kallikrein Panel, and MRI Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality 

Neurodevelopmental Effects of Antenatal IV Magnesium Sulfate Between 30-34 Weeks' Gestation

Download our free app to listen on your phone