Dr. Nicolas Bonnet introduces the concept of the "gut musculoskeletal axis," emphasizing the role of the gut microbiome in child musculoskeletal health. He highlights microbiome-driven mechanisms, including short-chain fatty acid production, mineral absorption regulation, and immune modulation, in bone and muscle development during early life. Based on the findings of a randomized controlled trial, he discusses how a young child formula with the synbiotic L. reuteri + GOS enhances bone strength, muscle function, and induction of microbiome changes in healthy young children.