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Nobel Winning Breakthrough: Unpacking Peripheral Immune Tolerance | GeneInCell
How FOXP3-defined Tregs prevent autoimmunity and shape therapy. We trace the discoveries by Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi, unpack Treg biology and assays, and explore translational angles—from autoimmune disease and transplantation to cancer immunotherapy and engineered Tregs. Educational content only; not medical advice.
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By Vinod Reddy LekkalaHow FOXP3-defined Tregs prevent autoimmunity and shape therapy. We trace the discoveries by Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi, unpack Treg biology and assays, and explore translational angles—from autoimmune disease and transplantation to cancer immunotherapy and engineered Tregs. Educational content only; not medical advice.