Welcome to the first episode of 2025 for The Brain Podcast - the official podcast of the journals Brain and Brain Communications.

This episode features a discussion with senior author Dr Frank Porreca of the Brain article entitled: Nociceptors are functionally male or female: from mouse to monkey to man?

Dr Porreca discusses important findings into the sexual dimorphic nature of nociception and how it could and indeed should affect clinical trial participant design, precision medicine and need for more sex specific studies to unravel the regulation of pain nociception in male and female individuals.

Check out the full article on the Brain website as part of the December 2024 issue: https://doi.org/10.1093/brain/awae179

This episode was co-hosted by Chaitra Sathyaprakash and Andreas Thermistocleous, edited and produced by Chaitra and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.