The DISRUPTED SCIENCE Podcast

November 12, 2025 — Interview with Jeremy Berg — "Fifty Shades of Jay" and Much More!


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Today, we’re talking with Jeremy Berg, a former editor of Science, former President of ASBMB, and former Director of the National Institute of General Medical Sciences (NIGMS) at the NIH.

Earlier this year, Berg grew alarmed at the nomination of Jay Bhattacharya as Director of the NIH, and began a correspondence with him after his confirmation. For a time, he documented this via his Bluesky account, which grew massively as a result.

Striking a calm, evidence-based tone, Berg often received no response from Bhattacharya. When he did, the responses seemed to bristle with political overtones. Berg published these correspondences in late Summer in PDF form under the title, “Fifty Shades of Jay.” He continues to update the document from time to time.

We wanted to talk with Jeremy about this, and given the recent spate of announcements about Director-level “hiring in a hurry” at the NIH — including a new Director of the NLM — we also wanted to discuss other aspects of MAHA-era science defunding, firings, and hirings as the US scientific establishment is turned upside-down. We also talk about diversity issues, with a particularly interesting angle coming to light.

It’s a fascinating interview throughout, which we close with our “Discoveries of the Week.”

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    The DISRUPTED SCIENCE PodcastBy Caldera Information Solutions LLC