Title: Anatomical Pathology Patient Interest Association (APPIA) TOPS Tissue Handling Guidelines illustrate an ongoing education initiative to improve the understanding of pre-analytical factors and promote standardization in tissue workflows.

Authors: Robert Lott, HTL(ASCP), Anatomical Pathology Patient Interest Association (APPIA), Raleigh, NC; Joshua Greenlee, MBA IASSC, HTL(ASCP)cm, Anatomical Pathology Patient Interest Association (APPIA), Raleigh, NC; Melissa Alexander, MD PhD, Anatomical Pathology Patient Interest Association (APPIA), Raleigh, NC; Jodi Barrientos, Anatomical Pathology Patient Interest Association (APPIA), Raleigh, NC; David Ferber, MD, Anatomical Pathology Patient Interest Association (APPIA), Raleigh, NC; Beth Sheppard, MBA, Anatomical Pathology Patient Interest Association (APPIA), Raleigh, NC; Shalini Singh, MD, Anatomical Pathology Patient Interest Association (APPIA), Raleigh, NC; Teri Saylor, Anatomical Pathology Patient Interest Association (APPIA), Raleigh, NC; Shanya Scott, Anatomical Pathology Patient Interest Association, Raleigh, NC; Erico von Bueren, MD PhD MOR, Anatomical Pathology Patient Interest Association (APPIA), Raleigh, NC