The National Nurse-Led Care Consortium (NNCC) is leading a two-year patient-centered initiative to cultivate a community of nursing stakeholders around substance use disorder care. The goal is to better understand optimal care delivery for individuals experiencing challenges related to substance use and persistent pain who have a heightened risk for infectious disease. In this episode, we speak with two patient advocates, Ivy Clark and Shelley Bastos, who share their perspectives on the role of nurses to address substance use disorder. We also hear from Kristine Gonnella, Senior Director of Strategic Initiatives at NNCC about the goals behind this project.