Jensen Huang's GTC March 2025 keynote showcases NVIDIA's advancements in AI and accelerated computing. Huang introduces their next-generation Blackwell architecture, emphasizing its significant performance leap for AI workloads, particularly reasoning and inference, within newly envisioned "AI factories." He details a multi-year hardware roadmap, including Blackwell Ultra and the future Vera Rubin and Rubin Ultra architectures, alongside innovations in data center infrastructure and networking, such as silicon photonics. The keynote also highlights NVIDIA's expanding role in enterprise AI with new DGX systems and open-source models, and their progress in robotics through physical AI, simulation tools like Omniverse and Cosmos, and the generalist robot foundation model Groot N1. Finally, Huang underscores the importance of their comprehensive software stack and collaborations across various industries to drive the AI revolution.