JACI: In Practice Editor-in-Chief, Michael Schatz, describes the October 2021 issue, the theme of which is “Vaccines.” Theme topics covered include SARS-CoV-2 vaccines in general, allergic reactions to SARS-CoV-2 vaccines, vaccine hesitancy, adverse reactions to vaccines, and influenza vaccines. Dr. Schatz then presents the Highlights of the Original Articles in the issue, which are on the topics of COVID-19, Asthma, Drug Allergy, Food Allergy, Hereditary Angioedema, Immunodeficiency, Insect Sting Allergy, and Rhinitis and Sinusitis. Read the issue: https://bit.ly/JAIPOct2021. Access JACI: In Practice’s entire library: https://www.jaci-inpractice.org