Sounds of Science

Off-Target, On-Point: How Retrogenix® Reduces Risk and Animal Use


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In this episode of Sounds of Science, learn how the Retrogenix® platform is reshaping drug development by identifying off-target risks earlier, reducing animal use, and gaining traction with regulators—now as part of the FDA’s ISTAND pilot program. Guests Nick Brown and Mark Aspinall-O’Dea from Charles River Discovery Services share real-world insights on their role in advancing NAMs and supporting safer, faster therapeutic development.

Show Notes 

  • Maximize Safer, Targeted Biologic Development with Smarter NAMs-Based Off-Target Screening 
  • Paving the Way for Enhanced Drug Development 
  • A Status Report on Cell-Based Protein Arrays 
  • Retrogenix® Human Protein Library 
  • Retrogenix®: The Screen Door of Drug Development 
  • Retrogenix® CAR Specificity Testing 
  • Charles River Launched New Retrogenix Non-Human Protein Library 
...more
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Sounds of ScienceBy Charles River

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