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Zofran
Indicationnausea/vomiting
Actionblocks effects of serotonin on vagal nerve and CNS
Therapeutic Classantiemetic
Pharmacologic Class5-HT3 antagonist
Nursing Considerations• administer slowly over 2-5 minutes – fatal QT prolongation and VTach, respiratory arrest • may cause headache, constipation, diarrhea, dry mouth • asses nausea and vomiting • assess for extrapyramidal symptoms • monitor liver function tests
By Jon Haws, RN CCRN Alumnus4.4
157157 ratings
Zofran
Indicationnausea/vomiting
Actionblocks effects of serotonin on vagal nerve and CNS
Therapeutic Classantiemetic
Pharmacologic Class5-HT3 antagonist
Nursing Considerations• administer slowly over 2-5 minutes – fatal QT prolongation and VTach, respiratory arrest • may cause headache, constipation, diarrhea, dry mouth • asses nausea and vomiting • assess for extrapyramidal symptoms • monitor liver function tests

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