A comprehensive overview of orofacial pain and headache, emphasizing the need for integrated classification and multidisciplinary treatment due to significant diagnostic overlap and complexity. It addresses the fundamental differences between acute and chronic pain, exploring their features, etiologies, and responses to various treatments. The material also examines the anatomy and neurophysiology of craniofacial pain, detailing sensory innervation and mechanisms like referred pain and central sensitization. Finally, the text extensively covers specific pain disorders, including temporomandibular joint (TMJ) dysfunction, migraine, trigeminal autonomic cephalgias (TACs), and neuropathic pain, alongside discussions on pharmacotherapy, assessment tools, and psychological factors.
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